The paper uses a linear regression model to examine the temporal and spatial disaggregation of Poland’s gross domestic product. The authors develop an approach based on estimating the structural parameters of linear regression in which annual regional GDP and its growth rate are used as dependent variables and annual national GDP and its changes play the role of explanatory variables. Pipień and Roszkowska estimate quarterly regional GDP and its changes as functions of the regression parameters. They compare alternative approaches with respect to the level of statistical uncertainty associated with the estimates. The sample covers the 1995-2012 period and the results obtained offer precise estimates of the rate of change in regional GDP, the authors say. Their research shows that regional differences in GDP growth are relatively small.